Prof.Dr.Heiko Neeb

 

Present academic position

Professor of Medical Physics
RheinAhrCampus Remagen
University of Applied Sciences Koblenz
53424 Remagen/Germany
Email: neebrheinahrcampus.de

 

Higher Education

1991-1993: Study of physics at the University of Mainz, Mainz (Germany)
1993-1996: Study of physics at the Technical University of München,
München(Germany)
1994-1995: Diploma thesis "Untersuchung seltener B-Meson Zerfälle mit dem
ALEPH Detektor bei LEP" at the Max-Planck-Institut für Physik,
Werner-Heisenberg-Institut, München (Supervisor: Prof. Norbert Schmitz)
1996: Graduation to Dipl.-Physiker
1996-1998: Doctoral thesis "Bestimmung der oberen Grenze des Ω0c
Wirkungsquerschnitts in Σ--Kern Reaktionen und Entwicklung eines
Verfahrens zur verbesserten Beurteilung statistischer Signifikanzen" at
the Max-Planck-Institut für Kernphysik, Heidelberg/Germany and CERN,
Geneva/Switzerland (Supervisor: Prof. Josef Pochodzalla)
1998: Promotion to Dr. rer. nat. at the University of Heidelberg

 

Career/employment

since 2008: Professor of Medical Physics at the University of Applied Sciences
Koblenz/Germany
2002-2008: Postdoctoral Fellow at the Institut für Medizin, Forschungszentrum
Jülich GmbH, Jülich/Germany (Director: Prof. Karl Zilles),
Development and clinical implementation of methods for quantitative
magnetic resonance imaging. Leader of the “Quantitative Imaging” Team
2000-2002: Senior Scientist at Biofrontera Pharmaceuticals AG, Leverkusen,
Team Leader, Development of statistical and bioinformatis based methods
for high-throughput gene-expression analysis.
1998-2000: Software-Engineer at Comsoft GmbH, Karlsruhe, Development of Air
Traffic Control Systems.

Research Interests:

• New MR Contrasts and Development of Fast Methods for Bound Water/Myelin Imaging.
• Neuroimaging of Multiple Sclerosis using Quantitative MRI.
• Quantum Mechanical Simulation of Tissue Relaxation Properties.
• Translation of New Imaging Approaches to Clinical Routine.
• Medical Informatics, Software Development
• Image Analysis, Development of Cluster Algorithms for Image Segmentation
and Classification.
• Physics

 

Publications

H.Neeb, J. Schenk and B. Weber.
MULTICENTRE ABSOLUTE MYELIN WATER CONTENT MAPPING: DEVELOPMENT OF A WHOLE BRAIN ATLAS AND APPLICATION TO LOW--GRADE MULTIPLE SCLEROSIS. NeuroImage:Clinical 1(1): 2012, 121-130.

H. Neeb.
DYNAMIC MODELLING OF NUCLEAR FUSION AS A NEW TOOL TO IDENTIFY SUBGROUPS IN MULTIPLE SCLEROSIS MAGNETIC RESONANCE IMAGING DATA. Lecture Notes in Engineering and Computer Science:
Proceedings of The World Congress on Engineering and Computer Science 2012, WCECS 2012, 24-26 October, 2012, San Francisco, USA, pp. 634-639.

V. Tonkova, D. Paulus and H. Neeb.
NUCLEAR POTENTIAL CLUSTERING AS A NEW TOOL TO DETECT PATTERNS IN HIGH DIMENSIONAL DATASETS. J. Phys.: Conf. Ser. 410:2013 012004.  doi:10.1088/1742-6596/410/1/012004

D. Frank, M. Rausch, V. Tonkova, V. Arhelger and H. Neeb.
DEVELOPMENT OF A QUANTITATIVE MYELIN WATER CONTENT ATLAS TO DETERMINE REGIONS OF DISTINCT DEMYELINATION IN LOW-GRADE MULTIPLE SCLEROSIS. Proceedings of the 43rd Annual Meeting of the German Society for Medical Physics (2012).

V. Tonkova, and H. Neeb.
NUCLEAR POTENTIAL CLUSTERING AS A NEW TOOL TO DETECT PATTERNS IN HIGH DIMENSIONAL DATASETS: APPLICATION TO QUANTITATIVE MR MAPS OF MULTIPLE SCLEROSIS. Proceedings of the 43rd Annual Meeting of the German Society for Medical Physics, Jena/Germany (2012).

V. Tonkova, V. Arhelger, J. Schenk and H. Neeb.
RAPID MYELIN WATER CONTENT MAPPING ON CLINICAL MR SYSTEMS. Z. Med. Phys 22(2): 2012, 133-142.

M-J. Kraus, H. Neeb, E.F. Strasser.
QUANTITATIVE ANALYSIS OF PLATELET SHAPE CHANGE DURING CONTACT ACTIVATION IN DIABETIC PATIENTS AND NORMAL PERSONS. Proceedings of the 56th Annual Meeting of the German Association of Hemostasis and Thrombosis. St. Gallen/Switzerland 2012.

D.L. Feis, H. Neeb, I. Weinreich.WAVELET-BASED TEXTURE ANALYSIS IN MULTIPLE SCLEROSIS USING QUANTITATIVE MRI. Proceedings of The Seventh IASTED International Conference on Signal Processing, Pattern Recognition and Applications, SPPRA 2010, Innsbruck.

T. Hilkert and H. Neeb.
QUANTITATIVE MR CORRELATION IMAGING IN MULTIPLE SCLEROSIS. In Hodap N, Hennig J and Mix M: Medizinische Physik 2010 (2010).

F. Kasten, V. Arhelger and H. Neeb.
QUANTITATIVE WATER CONTENT MAPPING USING MRI. In Hodap N, Hennig J and Mix M: Medizinische Physik 2010 (2010).

V. Tonkova, M.S. Lafontaine, B. Weber and H. Neeb.
DEVELOPMENT OF QUANTITATIVE T1, T2* AND TOTAL WATER CONTENT BRAIN ATLASES AT 3T. In Hodap N, Hennig J and Mix M: Medizinische Physik 2010 (2010).

C. Gasparovic, H. Neeb, DL Feis, E. Damaraju, H Chen, MJ Doty, DM South, PG Mullins, HJ Bockholt, NJ Shah.
QUANTITATIVE SPECTROSCOPIC IMAGING WITH IN SITU
MEASUREMENTS OF TISSUE WATER, T1, T2 AND DENSITY. Magn Reson Med. 62(3):2009, 583-90.

V. Ermer, H. Neeb and N.J. Shah
DEVELOPMENT AND EVALUATION OF A QUANTITATIVE BRAIN ATLAS AT 1.5T AND ITS APPLICATION TO MS. Proceedings of the 17th International Society for Magnetic Resonance in Medicine (ISMRM) Honolulu, USA, 2009.

D.R. Lang1, V. Ermer, N.J. Shah and H. Neeb
SEGMENTATION OF MULTIPLE SCLEROSIS LESIONS USING QUANTITATIVE MRI. Proceedings of the 17th International Society for Magnetic Resonance in Medicine (ISMRM) Honolulu, USA, 2009.

H. Neeb, V. Ermer, T. Stoecker, K. Zilles, and N.J. Shah.
FAST HIGH-RESOLUTION MAPPING OF CEREBRAL WATER CONTENT WITH FULL BRAIN COVERAGE. NeuroImage 42:2008, 1094-1109.

Shah NJ, Neeb H, Kircheis G, Engels P, Häussinger D, and Zilles K.
QUANTIATIVE CEREBRAL WATER CONTENT MAPPING IN HEPATIC ENCEPHALOPATHY. NeuroImage 41:2008, 706-717.

N.J. Shah, I.A. Gilani, H. Neeb, A.M. Oros-Peusquens.
MULTI-CHANNEL LINE-SHARING FOR RAPID T1 MAPPING. Proceedings of the 16th International Society for Magnetic Resonance in Medicine (ISMRM) Toronto, CA, 2008.

N.J. Shah, H. Neeb, G. Kircheis, P. Engels, D. Haeussinger, K. Zilles.
QUANTITATIVE CEREBRAL WATER CONTENT MAPPING IN HEPATIC ENCEPHALOPATHY. J Hepatology 46:2007, S86

H. Neeb, and N.J. Shah.
ENHANCING THE PRECISION OF QUANTITATIVE WATER CONTENT MAPPING BY OPTIMISING SEQUENCE PARAMTERS. Magnetic Resonance In Medicine 56:2006, 224-229.

H. Neeb, K. Zilles, and N.J. Shah.
A NEW METHOD FOR FAST QUANTITATIVE MAPPING OF ABSOLUTE WATER CONTENT IN VIVO. NeuroImage 31:2006, 1156-1168.

H. Neeb, K. Zilles, and N.J. Shah.
FULLY AUTOMATED DETECTION OF CEREBRAL WATER CONTENT CHANGES: STUDY OF AGE- AND GENDER-RELATED H2O PATTERNS WITH QUANTITATIVE MRI. NeuroImage 29:2006, 910-922.

S. Wildenburg, H. Neeb and N.J. Shah.
BRAIN TUMOUR SEGMENTATION WITH QUANTITATIVE MRI. In Hartmann U. et al.: Aktuelle Methoden der Laser- und Medizintechnik. VDE Verlag, 2005: 78-84.

H. Neeb, K. Zilles, N.J. Shah.
PRÄZISE QUANTIFIZIERUNG DES ABSOLUTEN WASSERGEHALTES IN VIVO. 31st. Annual Meeting of the German Society of Neurosurgery. Dresden, Germany, October 2005.

H. Neeb, K. Zilles, N.J. Shah.
AUTOMATED DETECTION OF QUANTITATIVE WATER CONTENT CHANGES: STUDY OF AGE- ND GENDER-RELATED CEREBRAL H2O PATTERNS. Proccedings of the 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine, Miami, FL, USA, 2005.

H. Neeb, G. Kircheis, D. Häussinger, K. Zilles and N.J. Shah.
QUANTITATIVE MEASUREMENT OF ABSOLUTE WATER CONTENT IN HEPATIC ENCEPHALOPATHY. Proccedings of the 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine, Miami, USA, 2005.

S.Wildenburg, H. Neeb and N.J. Shah.
BRAIN TUMOUR SEGMENTATION WITH QUANTITATIVE MRI. Proccedings of the 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine, Miami, USA, May 2005.

H. Neeb, K. Zilles, and N.J. Shah.
A NEW METHOD FOR FAST QUANTITATIVE MAPPING OF ABSOLUTE WATER CONTENT IN VIVO. Proccedings of the 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine, Miami, USA, 2005.

N.J. Shah, H. Neeb, G. Kircheis, D. Häussinger, and K. Zilles.
QUANTITATIVE MAPPING OF ABSOLUTE WATER CONTENT AND T1 IN HEPATIC ENCEPHALOPATHY. Proccedings of the 12th International Symposium on Hepatic Encephalopathy and Nitrogen Metabolism, Schloss Burg (2005).

R. Seitz, J.P. Nickel, M. Sabel, R. Kleiser, S. Joergens, L. Tellmann, H. Neeb, T. Stoecker, N.J. Shah, D. Pauleit, G. Stoffels, K.J. Langen, P. Indefrey, W. Stummer, and H.Herzog:
PRESURGICAL MULTIMODAL IMAGING IN PATIENTS WITH CEREBRAL TUMORS. Klinische Neurophysiologie 35(3):2004, 262.

H. Neeb , T. Dierkes, K. Zilles, N.J. Shah:
QUANTITATIVE MEASUREMENT OF LOCALISED WATER CONTENT USING THE TAPIR PULSE SEQUENCE. Proccedings of the 10th Annual Meeting of the Organisation for Human Brain Mapping, Budapest, Hungary, 2004.

J. Nickel, R. Kleiser, S. Joergens, H. Neeb, T. Stoecker, N.J. Shah, P. Indefrey, R.J. Seitz.
SECONDARY, FULL COMPENSATORY BILATERAL REPRESENTATION OF SPEECH IN A RIGHT-HANDED FEMALE WITH A FRONTO-TEMPORAL TUMOR. Proccedings of the 10th Annual Meeting of the Organisation for Human Brain Mapping, Budapest, Hungary, 2004.

H. Neeb, T. Dierkes and N. J.Shah.
QUANTITATIVE T1 MAPPING AND ABSOLUTE WATER CONTENT MEASURMENT USING MRI. International Congress Series 1265:2004, 113-123.

T. Dierkes, H. Neeb and N. J.Shah:
DISTORTION CORRECTION IN ECHO PLANAR IMAGING, AND QUANTITATIVE T2* MAPPING. International Congress Series 1265:2004, 181-185.

N. J. Shah, H.Neeb, M.Zaitsev, S. Steinhoff, G. Kircheis, K. Amunts, D. Häussinger, and K. Zilles: QUANTITATIVE T1 MAPPING OF HEPATIC ENCEPHALOPATHY USING MAGNETIC RESONANCE IMAGING. Hepatology 38:2003, 1219-1226.

M.I. Adamovich et al., The WA89 Collaboration:
SPECTRA AND CORRELATIONS OF LAMBDA AND LAMBDA PRODUCED IN 340-GEV/C SIGMA- + C AND 260-GEV/C N+C INTERACTIONS. Phys.Rev.C 65;2002: 042202.

M.I. Adamovich et al., The WA89 Collaboration:
DETERMINATION OF THE TOTAL C ANTI-C PRODUCTION CROSSSECTION IN 340-GEV/C SIGMA- NUCLEUS INTERACTIONS. Eur.Phys.J. C 13;2000:247-254.

M.I. Adamovich et al., The WA89 Collaboration:
PRODUCTION OF XI* RESONANCES IN SIGMA- INDUCED REACTIONS AT 345-GEV/C. Eur.Phys.J. C 11;1999:271-278.

M.I. Adamovich et al., The WA89 Collaboration.
CHARGE ASYMMETRIES FOR D, D(S) AND LAMBDA(C) PRODUCTION IN SIGMA- NUCLEUS INTERACTIONS AT 340-GEV/C. Eur.Phys.J. C 8;1999:593-601.