Forschung & Projekte Veröffentlichungen / Publikationen

• Zange J., Molitor S., Illbruck A., Müller K., Kohl-Bareis M., Rittweger J. (2014): Vibration of the unloaded lower leg extrudes venous blood from the calf muscle without a perceptible reflex contraction and without causing vasodilation. Eur J Appl Physiol 114:1005-1012 DOI 10.1007/s00421-014-2834-9
• Gramer M., Feuerstein D., Steimers A., Takagaki M., Kumagai T., Sué M., Vollmar S., Kohl-Bareis M., Backes H., Graf R. (2014): Device for simultaneous positron emission tomography, laser speckle imaging and RGB reflectometry: Validation and application to cortical spreading depression and brain ischemia in rats. Neuroimage 94:250-62. doi: 10.1016
• Steimers A., Steinke S., Ima H., Graf R., Graser R., Kohl-Bareis M. (2014): Spectroscopic hyperspectral imaging of haemoglobin oxygenation. Adv. Exp. Biol. Med, accepted for publication
• Steimers A., Vafiadou M., Koukourakis G., Geraskin D., Neary P., Kohl-Bareis M. (2014): Muscle oxygenation during running assessed by broad band NIRS. Adv. Exp. Biol. Med, accepted for publication
• Steimers A., Farnung W., Kohl-Bareis M. (2014): Efficient algorithm for the temporal and spatial based calculation of speckle contrast. Adv. Exp. Biol. Med, accepted for publication
• Härtel S., Kutzner C., Westphal E., Limberger M., Burkart M., Ebner-Priemer U., Kohl-Bareis M., Bös K. (2014): Effects of endurance exercise training and Crataegus extract WS® 1442 in patients with heart failure with preserved ejection fraction – a randomized controlled trial, Sports, accepted for publication.
• Sørensen H., Rasmussen P., Siebenmann C., Zaar M., Hvidtfeldt M., Ogoh S., Sato K., Kohl-Bareis M., Secher N. H., Lundby C. (2014): Cutaneous oxygenation influences INVOS-4100 and NIRO-200NX near infrared spectroscopy determined frontal lobe oxygenation. Clin Physiol Funct Imaging. 35, 177-84. Doi:10.1111/cpf.12142

• K. Henn: A spectroscopic approach to monitor the cut processing in pulsed laser osteotomy, Lasers in Medical Science, Januar 2013, ISSN 0268-8921, Springer Verlag
• Leuchs AK & Neuhäuser M (2013): A modified combination test for the analysis of a clinical trial when a protocol amendment changed the inclusion criteria, Journal of Statistical Computation and Simulation 83, 823-834
• Ruxton GD & Neuhäuser M (2013): Review of alternative approaches to calculation of a confidence interval for the odds ratio of a 2x2 contingency table, Methods in Ecology and Evolution 4, 9-13
• Wendt D, Kahlert P, Lenze T, Neuhäuser M, et al. (2013): Management of high-risk patients with aortic stenosis and coronary artery disease, Annals of Thoracic Surgery 95, 599-605.
• Ruxton, G.D., Neuhäuser, M. & Pewsey, A.: Circular Statistics in R. To appear, in 2013, Oxford University Press
• Gerz E., Geraskin D.,Franke J., Platen P., Steimers A., Kohl-Bareis M., (2013): Tissue Oxygenation during Exercise Measured with NIRS: Reproducibility and Influence of Wavelengths, Adv Exp Med Biol. 2013;789:171-7
• Grieger S., Geraskin D., Steimers A., Kohl-Bareis M. (2013): Analysis of NIRS based Muscle Oxygenation Parameters by Inclusion of Adipose Tissue Thickness, Adv Exp Med Biol. 2013;789:131-6
• Steimers A., Gramer M., Takagaki M., Graf R., Lindauer U., Kohl-Bareis M. (2013): Simultaneous imaging of cortical blood flow and haemoglobin concentration with LASCA and RGB reflectometry, Adv Exp Med Biol. 2013;789:427-33.
• Steimers A., Steinke S., Kohl-Bareis M. (2013): Wavelength selection for the improvement of the signal to noise ratio for imaging of haemoglobin oxygenation with RGB reflectometry, Adv Exp Med Biol. 2013;789:405-10
• Sperlich B., Born D.-P., Swarén M., Kilian Y., Geesmann B., Kohl-Bareis M., Holmberg H.-Ch. (2013): Is leg compression beneficial for alpine skiers? BMC Sports Science, Medicine and Rehabil.5(1) 18
• Steimers A., Farnung W., Kohl-Bareis M. (2013): Efficient algorithm for the temporal and spatial based calculation of speckle contrast. Proc. SPIE 8801 DOI: 10.1117/12.2031834
• Steimers A., Pinkernell S., Lindauer U., Kohl-Bareis M. (2013): Simultaneous imaging of cortical haemoglobin concentration and blood flow with RGB reflectometry and LASCA during cortical activation in rats. Proc. SPIE 8804 DOI: 10.1117/12.2031833
• Steimers A., Steinke S., Kohl-Bareis M. (2013): Wavelength selection for the improvement of the signal to noise ratio for imaging of haemoglobin oxygenation with RGB reflectometry Proc. SPIE 8799 DOI: 10.1117/12.2031835
• Beijer A., Rosenberger A., Weber T., Gehlert S., Herrera F., Degens H., Kohl-Bareis M., Zange J., Bloch W., Rittweger J. (2013): The functional state of skeletal muscle circulation adapts differently to a resistive exercise intervention with and without superimposed whole-body vibrations. Submitted J. Appl. Physiol.
  
  

• J. Overbuschmann, J. Hengster, S. Irsen, T. Wilhein: Fabrication of Fresnel zone plates by ion-beam lithography and application as objective lenses in extreme ultraviolet microscopy at 13 nm wavelength, Optics Letters, Vol. 37, Issue 24, pp. 5100-5102 (2012)
• Neuhäuser M (2012): Nonparametric statistical tests: A computational approach, Chapman & Hall/CRC, Boca Raton
• Neuhäuser M (2012): Biostatistik. In: Botzenhart C, et al. (eds.): Gesell­schaftliche Relevanz von Wissenschaft und Forschung: Ein interdiszipli­närer Diskurs, Ferdinand Schöningh, Paderborn, pp. 236-246.
• Thielmann M, Pasa S, Wendt D, Price V, Marggraf G, Neuhäuser M, et al. (2012): Prognostic significance of cardiac troponin I on admission for surgical treatment of acute pulmonary embolism: a single-centre experience over more than 10 years. European Journal of Cardio-thoracic Surgery 42, 951-957.
• Kohl-Bareis M. (2012): NIRS: Theoretical Background and Practical Aspects. in: Functional Imaging in Exercise Sciences, editors: Boecker H., Hillmann Ch., Scheef L., Springer Verlag 2012. ISBN-13: 978-1461432920
• Sørensen H, Secher N.H., Siebenmann C., Nielsen H.B., Kohl-Bareis M., Lundby C., Rasmussen P. (2012): Cutaneous vasoconstriction explains the reduction in NIRS-determined cerebral oxygen saturation during administration of norepinephrine in healthy subjects. Anesthesiology 117(2): 263-270.
  
  

• J. Ewald, T. Wilhein: Source Size Characterization of a Microfocus Xray Tube Used for InLine PhaseContrast Imaging, AIP Conf. Proc. 1365, 81 (2011)
• J. Lenz, N. Krupp, T. Wilhein, and S. Irsen: Nanofabrication of Optical Elements for SXR and EUV Applications: Ion Beam Lithography as a New Approach, AIP Conf. Proc. 1365, 104 (2011)
• M. Benk, K. Bergmann, A. Querejeta-Fernández, S. Srivastava, N.A. Kotov,D. Schaefer, and T. Wilhein: Soft X-Ray Microscopic Investigation on Self Assembling Nanocrystals, AIP Conf. Proc. 1365, 433 (2011)
• R. Heine, T. Gorniak, T. Nisius, C. Christophis, M.E. Pettit, F. Staier, T. Wilhein, S. Rehbein, M. Grunze, und A. Rosenhahn: Digital in-line X-ray holography with zone plate, Ultramicroscopy111 (8),1131-1136 (2011)
• R. Lebert, A. Farahzadi, W. Diete, D.Schäfer, C. Phiesel, T. Wilhein, S. Herbert, A. Maryasov, L. Juschkin, D. Esser, M. Hoefer und D. Hoffmann Actinic: EUV-mask metrology: tools, concepts, components, SPIE 7985, 79850B (2011)
• N. Yu. Orlov, O. B. Denisov, O. N. Rosmej, D. Schäfer, T. Nisius, T. Wilhein, N. Zhidkov, A. Kunin, N. Suslov, A. Pinegin, V. Vatulin and Y. Zhao: Theoretical and experimental studies of material radiative properties and their applications to laser and heavy ion inertial fusion, Laser and Particle Beams 29, 69-80 (2011)
• O.N. Rosmej, V. Bagnoud, U. Eisenbarth, V. Vatulin, N. Zhidkov, N. Suslov, A. Kunin, A. Pinegin, D. Schäfer, T. Nisius, T. Wilhein, T. Rienecker, J. Wiechula, J. Jacoby, Y. Zhao, G. Vergunova, N. Borisenko und N. Orlow: Heating of low-density CHO-foam layers by means of soft X-rays, Nucl. Instr. and Meth. A, doi:10.1016/j.nima.2011.01.167 (2011)
• Neuhäuser M (2011): Permutation tests (pp. 1060-1062); Wilcoxon-Mann-Whitney test (pp. 1656-1658); Wilcoxon-signed-rank test (with D. Rey, pp. 1658-1659), Lodric M (ed.): International Encyclopedia of Statistical Science, Springer-Verlag, Heidelberg
• Neuhäuser M, Leuchs AK & Ball D (2011): A new location-scale test based on a combination of the ideas of Levene and Lepage, Biometrical Journal 53, 525-534
• Warnecke J., Wendt Th., Schak M., Schiffer Th., Bloch W., Kohl-Bareis M. (2011): Evaluation of haemoglobin changes of skin and muscle tissue of the calf induced by topical application of a nonivamide / nicoboxil cream. Proc. SPIE 8087
• Steimers A., Gramer M., Takagaki M., Graf R., Kohl-Bareis M. (2011): Simultaneous imaging of haemoglobin oxygenation and blood flow with RGB reflectometry and LASCA during stroke in rats. Proc. SPIE 8087
• Liu H., Kohl-Bareis M., Huang X. (2011): Design of a tissue oxygenation monitor and verification on human skin. Proc. SPIE 8087 80871Y-1
• Härtel S., Kutzner C., Schneider D., Grieger S., Neumaier M., Kohl-Bareis M. (2011): Oxygenation of the calf muscle during an incremental, intermittent walking exercise assessed by NIRS. Proc. SPIE 8087
• Gao L., Gramer M., Kohl-Bareis M., Cooper Ch. E., Elwell C., Leung T. S., Tachtsidis I (2011): Effects of assuming constant optical scattering on haemoglobin concentration measurements using NIRS during a Valsalva Manoeuvre. Adv Exp Med Biol. 915: 15-20
  
  

• A. P. Mancuso, Th. Gorniak, F. Staier, O. M. Yefanov, R. Barth, C. Christophis, B. Reime, J. Gulden, A. Singer, M. E. Pettit, Th. Nisius, Th. Wilhein, C. Gutt, G. Grübel, N. Guerassimova, R. Treusch, J. Feldhaus, S. Eisebitt, E. Weckert, M. Grunze, A. Rosenhahn and I. A. Vartanyants
  Coherent imaging of biological samples with femtosecond pulses at the free-electron laser
  FLASH New Journal of Physics 12 (2010) 035003 (14pp)
• C. Gutt, S. Streit-Nierobisch, L. M. Stadler, B. Pfau, C. M. Günther, R. Könnecke, R. Frömter, A. Kobs, D. Stickler, H. P. Oepen, R. R. Fäustlin, R. Treusch, J. Feldhaus, E. Weckert, I. A. Vartanyants, M. Grunze, A. Rosenhahn, T. Wilhein, S. Eisebitt, G. Grübel
  Single-pulse resonant magnetic scattering using a soft x-ray free-electron laser
  Phys. Rev. B, 81 (10), 100401 (2010) 
• Füchtemeier M., Leithner Ch., Offenhauser N., Foddis M., Kohl-Bareis M., Dirnagl U., Lindauer U., Royl G. (2010): Elevating intracranial pressure reverses the decrease in deoxygenated hemoglobin and abolishes the post-stimulus overshoot upon somatosensory activation in rats Neuroimage.
  15, 52(2): 445-54
• Leithner C, Royl G, Offenhauser N, Füchtemeier M, Kohl-Bareis M, Villringer A, Dirnagl U, Lindauer U. (2010): Pharmacological uncoupling of activation induced increases in CBF and CMRO(2). J. Cerebral Blood Flow Metab. 30, 311-322
• Lindauer U., Leithner Ch., Kaasch H., Rohrer B., Foddis M., Füchtemeier M., Offenhauser N., Steinbrink J., Royl G., Kohl-Bareis M., Dirnagl U. (2010): Neurovascular coupling in rat brain operates independent of hemoglobin deoxygenation J. Cerebral Blood Flow and Metabolism, 30, 757-68
• Tachtsidis I., Gao L., Leung T. S., Kohl-Bareis M., Cooper Ch. E., Elwell C. E. (2010): A Hybrid Multi-Distance Phase and Broadband Spatially Resolved Spectrometer and Algorithm for Resolving Absolute Concentrations of Chromophores in the Near-Infrared Light Spectrum. Adv. Exp. Med. Biol. 662: 169-75
  
  

• Geraskin D., Boeth H., Kohl-Bareis M. (2009): Optical measurement of the Adipose Tissue Thickness and Comparison with Ultrasound, MRI and Calliper. J. Biomed. Opt., 14(4):044017.
• Gerz E., Geraskin D., Neary P., Franke J., Platen P., Kohl-Bareis M. (2009): Tissue Oxygenation during Exercise Measured with NIRS: A Quality Control Study SPIE 7368-58
• Steimers A., Gramer M., Ebert B., Füchtemeier M., Royl G., Leithner C., Dreier J. P., Lindauer U., Kohl-Bareis M. (2009): Imaging of Cortical Haemoglobin Concentration with RGB Reflectometry Proc. SPIE 7368-30
• Koukourakis G., Vafiadou M., Steimers A., Geraskin D., Neary P., Kohl-Bareis M. (2009): Using broadband spatially resolved NIRS to assess muscle oxygenation during altered running protocols Proc. SPIE 7368-73

Royl G., Füchtemeier M., Leithner C., Megow D., Offenhauser N., Steinbrink J., Kohl-Bareis M., Dirnagl U., Lindauer U. (2008): Hypothermia effects on neurovascular coupling and cerebral metabolic rate of oxygen Neuroimage, 40(4):1523-32

• Advances in Medical Engineering, Springer Proceedings in Physics, Vol. 114 (2007) Th. Buzug, D. Holz, S. Weber, J. Bongartz, M. Kohl-Bareis, U. Hartmann
• Soschinski J., Ben Mine L., Geraskin D., Bennink G., Kohl-Bareis M. (2007): Cerebral Oxygenation Monitoring during Cardiac Bypass Surgery in Infants with Broad Band Spatially Resolved Spectroscopy Proc. SPIE 6629 ‘Diffuse Optical Imaging of Tissue’
• Geraskin D., Boeth H., Kohl-Bareis M. (2007): Spectroscopic measurement of Adipose Tissue Thickness and comparison with Ultrasound Imaging Proc. SPIE 6629 ‘Diffuse Optical Imaging of Tissue’
• Geraskin D., Platen P., Franke J., Kohl-Bareis M.(2007): Algorithms for Muscle Oxygenation Monitoring corrected for Adipose Tissue Thickness Proc. SPIE 6629 ‘Diffuse Optical Imagng of Tissue’
• Soschinski J., Fischer U., Geraskin D., Mehlhorn U., Bennink G., Kohl-Bareis M. (2007): Cerebral Oxygenation Monitoring during Cardiac Bypass Surgery in Infants with Broad Band Spatially Resolved Spectroscopy Advances in Medical Engineering, Springer Proceedings in Physics, Vol. 114
• Geraskin D., Platen P., Franke J., Kohl-Bareis M. (2007): Algorithms for Muscle Oxygenation Monitoring corrected for Adipose Tissue Thickness Advances in Medical Engineering, Springer Proceedings in Physics, Vol. 114
• Dreier J. P., Kleeberg J., Alam M., Major S., Kohl-Bareis M., Petzold G.C., Victorov I., Dirnagl U., Obrenovitch T. P., Priller J. (2007): Endothelin-1-induced spreading depression in rats is associated with a microarea of selective neuronal necrosis. Exp Biol. Med., 232(2):204-13

Royl G., Leithner Ch., Sellien H., Müller J. Ph., Megow D., Steinbrink  J., Kohl-Bareis M., Dirnagl U., Lindauer U. (2006): Functional Imaging with Laser Speckle Contrast Analysis: Vascular Compartment Analysis and Correlation with Laser Doppler Flowmetry and Somatosensory Evoked Potentials, Brain Res. 22;1121(1):95-103

• Aktuelle Methoden der Laser- und Medizintechnik, VDI-Verlag ISBN 3-8007-2838-9 (2005) Editors: U. Hartmann, M. Kohl-Bareis, P. Hering, G. Lonsdale, J. Bongartz, T. Buzug
• Kohl-Bareis M., O. Rohm, Ch. Andre, P. Neary (2005): Optische Messung der Sauerstoffsättigung des Hämoglobins von Gehirn und Muskel, in: Aktuelle Methoden der Laser- und Medizintechnik, VDI-Verlag ISBN 3-8007-2838-9
• Buzug T, Kohl-Bareis M. (2005): Medical Imaging in the 1012 Hz - 1014 Hz Domain. Conf Proc IEEE Eng Med Biol Soc. 2:1728-31
• Rohm O., Andre Ch., Neary P., Kohl-Bareis M. (2005): Muscle oxygenation and blood content of muscle at rest and during exercise assessed by near-infrared spectroscopy. In: Aktuelle Methoden der Laser- und Medizintechnik, VDI-Verlag ISBN 3-8007-2838-9
• Buzug T. M., Holz D., Kohl-Bareis M., Schmitz G. (2005): Perspectives of Non-Standard Medical Imaging Modalities. In: Aktuelle Methoden der Laser- und Medizintechnik, VDI-Verlag ISBN 3-8007-2838-9, 22-27.
• Kohl-Bareis M., Lindauer U., Leithner Ch., Sellien H., Royl G., Dirnagl U. (2005): Funktionelle Neurovaskuläre Kopplung im Gehirn der Ratte. In: Aktuelle Methoden der Laser- und Medizintechnik, VDI-Verlag ISBN 3-8007-2838-9
• Geraskin D., Platen P., Franke J., Andre Ch., Bloch W., Kohl-Bareis M. (2005): Muscle Oxygenation during exercise under hypoxic conditions assessed by spatial-resolved broad-band NIR spectroscopy SPIE 5859OL
• Kohl-Bareis M., Gürtler R., Geraskin D., Leithner Ch., Lindauer U., Royl G., Selien H., Dirnagl U. (2005): System for the Measurement of Blood Flow and Oxygenation in Tissue Applied to Neurovascular Coupling in Brain SPIE 5859
• Geraskin D., Platen B., Franke J., Kohl-Bareis M. (2005): Algorithms for Muscle oxygenation monitoring corrected for adipose tissue thickness. Journal of Polish Academy of Science Opt. Meth. Med. Diagn. Conf., 33 - 39

• Uludag K., Steinbrink J., Kohl-Bareis M., Wenzel R., Villringer A., Obrig H. (2004): Cytochrome-c-oxidase redox changes during visual stimulation measured by near-infrared spectroscopy cannot be explained by a mere cross talk artefact. Neuroimage 22(1):109-19
• Rohm O., Gürtler R., Kohl-Bareis M. (2004): Evaluation of muscle oxygenation based on spatial-resolved broad band and time-resolved spectroscopy Biomedical Topical Meeting, OSA Technical Digest, SH2

• Physikalische Methoden der Laser- und Medizintechnik, VDI-Verlag (2003)
  Editors: T. M. Buzug, U. Hartmann, A. Hülster, M. Kohl-Bareis, T. Wilhein
• Kohl-Bareis M., Buckow C., Zank H., Obrig H., Villringer A. (2003): Optical Imaging of Cortical Activation. In: Physikalische Methoden der Laser- und Medizintechnik, VDI-Verlag Editors: T. M. Buzug, U. Hartmann, A. Hülster, M. Kohl-Bareis, T. Wilhein, 44-50.
• Steinbrink J., Uludag K., Obrig H., Kohl-Bareis M., Villringer A. (2003): Tiefenaufgelöste Nahinfrarot-spektroskopie am Kopf des Erwachsenen. In: Physikalische Methoden der Laser- und Medizintechnik, VDI-Verlag, Editors: T. M. Buzug, U. Hartmann, A. Hülster, M. Kohl-Bareis, T. Wilhein
• Syré F., Obrig H., Steinbrink S., Kohl M., Wenzel R., Villringer A (2003): Are VEP Correlated Fast Optical Changes Detectable in the Adult by Non Invasive Near Infrared Spectroscopy (NIRS)? Adv. Exp. Med. 530, 421-31
• Kohl M., Buckow C., Zank H., Obrig H., Villringer A., NIRS (2003): Topographic Imaging of Cortical Activation. Proceedings of the Polish Academy of Sciences “Laser–doppler flowmetry and near infrared spectroscopy in medical diagnosis”, ed. R. Maniewski, G. Nilsson, H. Rinneberg, 57-65.
• Lindauer U. P., Gethmann J., Kühl M., Kohl-Bareis M., Dirnagl U. (2003): Neuronal activity induced changes of local cerebral microvascular blood oxygenation in the rat: Effect of systemic hyperoxia or hypoxia Brain Research 975, 135-40
• Steinbrink J. Kempf F., Schreiber S., Uludag K., Kohl M., Valdueza J. M., Villringer A., Obrig H. (2003): Functional brain imaging by CW-NIRS coregistered by blood flow monitors SPIE Vol. 5138, 131

• Uludag K., Kohl M., Steinbrink J., Obrig H., Villringer A. (2002): Crosstalk in the Lambert-Beer calculation for near-infrared wavelength estimated by Monte simulations. J. Biomed. Opt. 7, 51-59
• Obrig O., Israel H., Kohl-Bareis M., Uludag R., Wenzel R., Müller B., Arnold G., Villringer A. (2002): Habituation of the Visually Evoked Potential (VEP) and its Vascular Response: Implications for Neurovascular Coupling in the Healthy Adult. Neuroimage 17, 1-8
• Kohl-Bareis M., Obrig H., Steinbrink J., Malak J., Uludag K., Villringer A. (2002): Non-invasive monitoring of cerebral blood flow by a dye bolus method: separation of brain from skin and skull signals J. Biomed. Optics 7, 464-470
• Lindauer U., Royl G., Leithner C., Kuhl M., Gethmann J., Kohl-Bareis M., Villringer A., Dirnagl U. (2002): Neuronal activation induced changes in microcirculatory hemoglobin oxygenation: to dip or not to dip, in: M. Tomita, I. Kanno, E. Hamel (Eds.), Brain Activation and CBF control, Vol. 1235, Elsevier, Amsterdam, 2002, pp. 137-144

• Wobst P., Wenzel R., Kohl M., Obrig H., Villringer A. (2001): Linear aspects of changes in blood oxygenation and cytochrome oxidase oxidation during brain activation. Neuroimage 13, 520-530
• Lindauer U., Royl G., Kühl M., Leithner Ch., Gold L., Gethmann J., Kohl M., Villringer A., Dirnagl U. (2001): No Evidence for Early Decrease in Blood Oxygenation in Rat Whisker Cortex in Response to Functional Activation Neuroimage 13, 988-1001
• Kohl M., Obrig H., Steinbrink J., Malak J., Uludag K., Villringer A. (2001): Non-invasive cerebral blood flow monitoring by a dye bolus method: separation of extra- and intracerebral  absorption changes by frequency-domain spectroscopy SPIE 4250, 296-300